Lars Dahlin
Biography
Current position
- Professor och överläkare i pediatrisk handkirurgi (Professor and senior consultant in pediatric hand surgery), Department of Hand Surgery Malmö-Lund, Skåne University Hospital, Lund University, Malmö, Sweden 2001/2006- (Professor and Chair 2009- )
- Guest professor, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden 2019 –
- External lecturer in Clinical Anatomy, Panum Institute, University of Copenhagen, Denmark (part time) 2005 – 2013
Clinical proficiency
- Consultant in Hand Surgery, Department of Hand Surgery, Malmö University Hospital, Malmö, Lund University, Sweden 1999-2001
- Senior resident in Hand Surgery, Department of Hand Surgery, Malmö University Hospital, Malmö, Lund University, Sweden 1994-1999
Administrative duties
- Scientific secretary, Swedish Society for Surgery of the Hand, 2001 – 2005
- Chairman, Swedish Society for Surgery of the Hand, 2009-2014
- Founder and previous contact person Clinical Network, Future Faculty, Lund University, 2003 – 2006
- Chairman, ALF committee for young researchers, Lund University, 2005- 2011
- Fernström Foundation 2009-2014
- Scientific Advisor, National Board of Health and Welfare, Sweden, 2009-
- Deputy head, Department of Clinical Sciences Malmö, 2012
- Board member Federation of European Societies for Surgery of the Hand (FESSH) and chairman for relationship committee (ExCom member 2015-2017), 2014-2017
- Prodean, Faculty of Medicine, 2013 – 2017
- Board member, European Society for the Study for Peripheral Nerve Repair and Regeneration (ESPNR), 2014 –
- Education in supervision for PhD students (handledarutbildning) Jan 31, 2005.
- Head of Department of Translational Medicine, Lund university, 2018 –2023
- Chairman of the Board for Animal Care, Lund university, (2013-2017) and operational manager (verksamhetsansvarig tillståndshavare) 2018 – 2023
- Clinical director (founder and previous chairman of steering committee) Wallenberg Centre for Molecular Medicine (WCMM), Lund University, 2018 –
- Member of the University Board, Lund University, 2020 –
- Principle investigator in several studies related to pharmacological substances.
- Have GCP training, 2002.
- Laboratory Animal Science for Researchers, 2013
Clinical trials
- Auxilium: 2008-2013
- PointX: 2010-2013
- Multicord: 2012-2013
- PharmaSurgics: 2009-2013
- Auxilum’s Real World: 2013-2019
- PMS Trial: 2016-2017
- VibroSense: 2014-2018
- Polyganics: 2018-2020
Research abroad
Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK (Dr. W. Graham McLean and Professor Alaistair Breckenridge), various periods during 1982-1987
Awards
- “Young successful scientist”, Faculty of Medicine, Lund University, University Hospital Malmö, Sweden, 2001
- “The Paul R. Manske Award for the 2014 article with the Greatest impact on the surgical care of the child’s hand”, 2014
- The International Dupuytren Award, 2016
Group structure
Ongoing activities as scientific mentor (main supervisor):
- Karolin Lundén, Department of Hand Surgery, Skåne University Hospital, Malmö (Hand infections – epidemiology, diagnosis and treatment with focus on flexor tenosynovitis an septic arthritis).
- Drifa Frostadottir, Department of Hand Surgery, Skåne University Hospital, Malmö (Nerve injuries – disability, symptoms and socioeconomic factors) Defence decided June 5th, 2024.
- Burcu Hazer Rosberg, Department of Hand Surgery, Skåne University Hospital, Malmö (Experimental nerve regeneration – new methods and relation to diabetes). Defence planned Dec 13th, 2024.
- Linnea Ekman, Department of Translational Medicine – Hand Surgery, Lund University, Malmö (Diabetic neuropathy). Defence planned Dec 11th, 2024.
Assistant supervisor for:
- Antonia Papadopoulou, Department of Clinical and Experimental Medicine, Linköping University, Linköping (Ulnar nerve compression – evaluation of outcome).
- Emanuel Istefan, Department of Clinical and Experimental Medicine, Linköping University, Linköping (Nerve tumors in upper extremity – symptoms, diagnosis, treatment, proteomics and patient experiences). Halftime control performed 2024)
Experimental Research Projects
At present, our experimental research projects are carried out at the Wallenberg Laboratory and CRC (Clinical Research Centre) at Skåne University Hospital, Malmö. Several of the staff members are active in various projects in this department. We welcome foreign visiting scientists in our laboratory. There is also a close collaboration with laboratories in Lund, especially Department of Biology. In addition, we are presently funded by EU to develop a new bioartificial tube to reconstruct nerve defects.
A significant part of hand injuries consists of peripheral nerve trauma varying from nerve compression lesions to complete transections and root avulsions at brachial plexus level. These injuries are extremely difficult to treat and the functional outcome is generally poor, especially in adults. Defects in nerve continuity require autologous nerve grafting.
Our project addresses peripheral nerve injuries from a holistic standpoint taking into account the whole perspective – “from molecule to man” – with special focus on pathophysiological events such as post traumatic metabolic shifts and phenotypic changes in neurons and non-neuronal cells after compression and transection in both healthy and diabetic models. We address methods aiming at finding alternatives to nerve grafts. Immunohistochemistry is used to study regulation of transcription factors (e.g. ATF-3, c-jun) and neuropeptides in neurons, early Schwann cell response (Erk 1/2 related to proliferation, HSP27 related to neuroprotection and cleaved caspase 3 as a marker for apoptosis) and nerve fibre regeneration. Such events are also investigated in diabetes.